The HRK has maintained regular relationships with various partners throughout Latin America since the middle of the 1990s, whereby the strongest contacts are to Argentina, Brazil, Chile, Columbia and Central America. The range of activities includes regular bilateral seminars on topics related to higher education policy, the conclusion of framework agreements on cooperation in higher education and supporting reform processes in higher education.
In addition, the HRK participates in multilateral cooperation projects in higher education between Germany (EU), and Latin America, and promotes the participation of Latin American partners in international conferences organised by the HRK. Latin America is also a particular focal point for the HRK's cooperation in developmental policy.